[PDF][PDF] ORIGINAL RESEARCH ARTICLE THE SHC PROTEIN RAI PROMOTES AN ADAPTIVE CELL SURVIVAL PROGRAM IN HYPOXIC NEUROBLASTOMA CELLS
M Criscuoli, I Filippi, D Osti, C Aldinucci, G Guerrini… - academia.edu
… Thus, our results suggest that different response to hypoxia maybe due, at least in part, to …
Distinct role of ShcC docking protein in the differentiation of neuroblastoma. Oncogene 28(5)…
Distinct role of ShcC docking protein in the differentiation of neuroblastoma. Oncogene 28(5)…
A review of the biomarkers with the potential to predict poor prognosis of neuroblastoma
L Li, M Lin, Z Lv, T Lin, C Liao, C Ye, Y Huang… - Authorea …, 2023 - techrxiv.org
… , location, degree of tumor differentiation, DNA content and different genetic alteration, among
… The mechanism of ShcC affecting the prognosis of NB may be inhibiting the differentiation …
… The mechanism of ShcC affecting the prognosis of NB may be inhibiting the differentiation …
Biomarkers in neuroblastoma: an insight into their potential diagnostic and prognostic utilities
F Shawraba, H Hammoud, Y Mrad, Z Saker… - … Treatment Options in …, 2021 - Springer
… of cellular functions such as cell proliferation, differentiation, … such as SHC-transforming
docking protein which is further implicated … a tumor suppressor in different cancers, its role as an …
docking protein which is further implicated … a tumor suppressor in different cancers, its role as an …
Defining pathological activities of ALK in neuroblastoma, a neural crest-derived cancer
AM Wulf, MM Moreno, C Paka… - International Journal of …, 2021 - mdpi.com
… differentiation, thus inducing the onset of neuroblastoma. … , which function as docking sites
for downstream targets [33]. … Nearly 30 different ALK fusion proteins have been described, …
for downstream targets [33]. … Nearly 30 different ALK fusion proteins have been described, …
A review of the biological and clinical implications of RAS-MAPK pathway alterations in neuroblastoma
V Mlakar, E Morel, SJ Mlakar, M Ansari… - Journal of Experimental …, 2021 - Springer
… of its deregulation in neuroblastoma, and current promising therapeutics targeting … cell
function as one of the central signaling axes that affect many different cellular functions (…
function as one of the central signaling axes that affect many different cellular functions (…
[HTML][HTML] Positive association of human SHC3 gene with schizophrenia in a Northeast Chinese Han population
Y Lv, Y Sun, GY Wang, J Yin, CJ Li, YY Luo… - Psychiatry …, 2020 - ncbi.nlm.nih.gov
… transforming protein 3 (SHC3), also known as N-Shc, ShcC … of cancer, including aggressive
neuroblastomas and human … different genetic models, and one of them showed difference …
neuroblastomas and human … different genetic models, and one of them showed difference …
Cancer predictive studies
… Neuroblastoma (NB) is clinically linked to distinct genomic … neuronal differentiation, including
neuroblastoma [57]. ZNF281 is highly expressed in stage 4 NB patients supporting a role of …
neuroblastoma [57]. ZNF281 is highly expressed in stage 4 NB patients supporting a role of …
Shc3 promotes hepatocellular carcinoma stemness and drug resistance by interacting with β-catenin to inhibit its ubiquitin degradation pathway
Y Liu, H Zhuang, F Cao, J Li, Y Guo, J Zhang… - Cell Death & …, 2021 - nature.com
… The SHC3 (known as Rai, N-Shc, ShcC) gene encodes for … In neuroblastoma cells, the
interplay between Shc3 and HIF-… assay of tumor tissues from different treatment groups of nude …
interplay between Shc3 and HIF-… assay of tumor tissues from different treatment groups of nude …
[HTML][HTML] The expression and prognostic value of Src homology 2 domain-containing transforming protein C3 (SHC3) and its potential role in colorectal cancer
C Zhao, J Zhang, J Ma, N Zhang… - Translational Cancer …, 2021 - ncbi.nlm.nih.gov
… protein C3 (SHC3; also known as Rai, N-Shc or ShcC) … We also measured SHC3 expression
in different CRC cell lines, … Aberrant SHC3 expression has been reported in neuroblastoma, …
in different CRC cell lines, … Aberrant SHC3 expression has been reported in neuroblastoma, …
[图书][B] Targeting ALK: An Explanation for PI3K Inhibition Induced Neuroblastoma Regression
Y Guo - 2020 - search.proquest.com
… to neuroblastoma with large variance among different age … in expression at the different
stages of differentiation. Many miRNAs … Several studies suggested ShcC be a potent substrate of …
stages of differentiation. Many miRNAs … Several studies suggested ShcC be a potent substrate of …